Opioid antagonist · generic Revia

Naltrexone.

Blocks the reward signal alcohol triggers, so the urge to keep drinking fades. Not addictive, not sedating.

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naltrexone

At a glance

Typical dose

50 mg daily

Your physician sets your dose.

Form

Tablet

Generic, from a licensed US pharmacy.

Regulatory status

FDA-approved for alcohol use disorder.

Used in: Drink less

What to expect

The timeline.

Week 1Mild nausea or headache can occur. Taking it with food helps.
Weeks 2 to 8Drinking tends to lose its pull.
OngoingLiver health reviewed. Many people continue for six to twelve months.

Common side effects

Nausea, headache, dizziness, tiredness.

Not suitable for

Anyone taking opioid pain medication, methadone or buprenorphine, or who has used opioids in the last 7 to 10 days. Not for acute hepatitis or liver failure.

This is a summary, not the full prescribing information. Read the leaflet that comes with your medication. Report side effects to your physician, or to the FDA at 1-800-FDA-1088.

The evidence

In the COMBINE trial of 1,383 people, naltrexone with medical management significantly reduced the risk of heavy drinking days (Anton et al., JAMA, 2006).

Published trial results, not okay. patient outcomes.

Naltrexone

$55/mo

Includes physician care, messaging, medication if prescribed, and free discreet shipping.

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